Investigation under way after Conn. commuter trains collide, send 60 to hospitals

Obama agenda seems to be weathering IRS targeting of conservative groups, other controversies

The estimated jackpot for Saturday's Powerball drawing has swelled to a record $600 million for the popular lottery game, but one official estimated today that if it goes unclaimed the prize would zoom to nearly $1 billion.

New IVF Treatment Promises Tripled Success Rate;'Star Trek' Filmmaker's Blockbuster Weekend

J.J. Abrams' latest sci-fi flick gets released to eager fans, recalling imagination at early age.

Air Force Chief of Staff Gen. Mark Welsh apologized Friday for comments he made last week that a “hook-up mentality” among America’s youth might be responsible for some sexual assaults in the military.  The comments were criticized by members of Congress and victims’ advocacy groups....

Twenty-five passengers suffered non-life-threatening injuries this evening when a commuter train derailed near Fairfield, Conn., and collided with another train, Fairfield, Conn., police said. Multiple reports of injuries prompted officials to scramble ambulances from all over the region to the Metro-North Railroad trains, both of...

Tennessee man is donating the $500 he won to his granddaughter's mission trip to Indonesia.

Chopard jewels worth $1 million were stolen from a hotel room safe during gala.

Investigator says he told top Treasury officials of IRS probe in June of campaign year 2012

Imagine growing older in the company of the ever-so-hip and handsome Ethan Hawke and the luminous Julie Delpy. Ardent fans watched their characters fall in love in Vienna in their 20s in the 1995 romantic drama, “Before Sunrise,” and reunite with passion tinged with regret...

The husband of a Pennsylvania doctor who died with "toxic levels of cyanide" in her system is being investigated as a person of interest, according to his attorney.

MOSCOW – In a breach of protocol, Russia has publicized the name of a man it says is the CIA station chief in Moscow. In comments to Russian media today, a spokesman for Russia’s Federal Security Service, or FSB (the successor to the KGB), confirmed...

Stocks finished out another record-breaking week. The Dow, S&P and NASDAQ stock indexes have posted four straight weeks of gains. The Dow Jones Industrial average ended the day up 121 points to close the week at 15,354. Year-to-date, the Dow is up 17 percent.  ...

Mini-movies of growing embryos could help boost the success of in vitro fertilization, a new study found. But the number of women who could benefit from the time-lapse technology is unclear.

OJ Simpson's ex-lawyer contradicts former football star's testimony on guns, legal strategy

Pa. coffee run leads to arrest for famed hatchet-wielding hitchhiker wanted in NJ killing

When Patrick King, 45, took a job at Arizona Shower Door six years ago as a crane operator, all he wanted was to work hard and bring home a good paycheck to support his wife and kids. Never in a million years did he imagine sitting next to his boss and being asked to do the unthinkable. Watch the full story on "20/20: Work War: How to Wage It, How to Win It" TONIGHT at 10 ET.

The former Chechen rebel who said his home was searched by the FBI in connection to the Boston Marathon bombing investigation said in a letter today he has "nothing to do with the terrible act in Boston."

Reported video of Toronto mayor smoking crack causes uproar in Canada; 'Ridiculous,' he says

Katie Holmes, the 34-year-old 'Dawson's Creek' star, sports wet hair and swimwear on the April 2013 cover of Allure.

Do you know how long it takes for a guy and a gal to "click" in the first stage of building a bond that may lead to a lasting relationship? Seconds, according to numerous studies.

Looks like Blue Ivy Carter could be a big sister soon! Days after the New York Post reported that Beyoncé and Jay-Z are expecting their second child, E! News followed suit, citing several sources. Pregnancy rumors reached an all-time high on Tuesday when the “Love On Top”...